Richard M Peek Selected Research

Type IV Secretion Systems

1/2021	Helicobacter pylori-Induced TLR9 Activation and Injury Are Associated With the Virulence-Associated Adhesin HopQ.
1/2019	Carcinogenic Helicobacter pylori Strains Selectively Dysregulate the In Vivo Gastric Proteome, Which May Be Associated with Stomach Cancer Progression.
1/2019	Targeted mobilization of Lrig1+ gastric epithelial stem cell populations by a carcinogenic Helicobacter pylori type IV secretion system.
10/2017	Helicobacter pylori Makes a Molecular Incision to Gain Epithelial Entry.
1/2017	Genetic Manipulation of Helicobacter pylori Virulence Function by Host Carcinogenic Phenotypes.
1/2015	Helicobacter pylori and CagA under conditions of iron deficiency.
7/2013	Induction of COX-2 expression by Helicobacter pylori is mediated by activation of epidermal growth factor receptor in gastric epithelial cells.
7/2005	Activation of beta-catenin by carcinogenic Helicobacter pylori.

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Richard M Peek Research Topics

Disease

53	Stomach Neoplasms (Stomach Cancer) 01/2022 - 04/2002
39	Neoplasms (Cancer) 01/2022 - 01/2002
35	Infections 01/2022 - 07/2002
32	Carcinogenesis 01/2022 - 07/2005
25	Inflammation (Inflammations) 01/2022 - 10/2002
11	Gastritis 11/2017 - 01/2002
6	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 09/2004
6	Adenocarcinoma 01/2020 - 06/2003
6	Carcinoma (Carcinomatosis) 01/2018 - 01/2008
5	Iron Deficiencies 01/2022 - 01/2013
5	Colitis 01/2021 - 06/2011
5	Metaplasia 01/2019 - 04/2009
4	Atrophy 12/2020 - 05/2005
2	Barrett Esophagus (Barrett's Esophagus) 11/2022 - 06/2011
2	Gastroesophageal Reflux (GERD) 11/2022 - 12/2005
2	Bacterial Infections (Bacterial Infection) 01/2019 - 11/2009
2	Stomach Ulcer (Gastric Ulcer) 11/2017 - 12/2016
2	Stomach Diseases 01/2016 - 01/2013
2	Colonic Neoplasms (Colon Cancer) 11/2013 - 08/2003
2	Neoplasm Metastasis (Metastasis) 01/2011 - 09/2004
2	Ulcer 12/2008 - 10/2005
1	Dysbiosis 11/2022
1	Liver Neoplasms (Liver Cancer) 11/2021
1	Duodenal Ulcer (Curling's Ulcer) 12/2020

Drug/Important Bio-Agent (IBA)

26	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2005
13	Oncogene Proteins (Oncogene Protein)IBA 01/2020 - 11/2011
11	CytokinesIBA 01/2020 - 01/2002
9	Cytotoxins (Cytolysins)IBA 10/2020 - 07/2005
9	Virulence Factors (Pathogenicity Factors)IBA 01/2020 - 04/2005
8	Anti-Bacterial Agents (Antibiotics)IBA 11/2022 - 07/2005
8	Type IV Secretion SystemsIBA 01/2021 - 07/2005
8	AcidsIBA 01/2021 - 05/2005
8	Biomarkers (Surrogate Marker)IBA 01/2021 - 06/2011
8	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 05/2005
6	SaltsIBA 10/2018 - 09/2012
6	Interleukin-8 (Interleukin 8)IBA 01/2018 - 10/2002
5	IronIBA 01/2019 - 01/2013
5	ErbB Receptors (EGF Receptor)IBA 01/2018 - 04/2009
5	Transcription Factors (Transcription Factor)IBA 01/2013 - 05/2005
4	EnzymesIBA 12/2019 - 10/2008
4	spasmolytic polypeptideIBA 01/2019 - 04/2009
4	Biological ProductsIBA 10/2016 - 06/2003
4	Adenosine Triphosphatases (ATPase)IBA 08/2015 - 07/2010
3	MagnesiumIBA 11/2021 - 01/2020
3	CarcinogensIBA 01/2019 - 01/2016
3	MicroRNAs (MicroRNA)IBA 02/2016 - 01/2011
3	Peptidoglycan (Murein)IBA 04/2015 - 03/2009
3	Polyamine OxidaseIBA 06/2014 - 11/2011
3	AntigensIBA 04/2007 - 04/2005
2	Tumor Suppressor Protein p14ARF (p14ARF)IBA 01/2022 - 01/2018
2	Levofloxacin (Levaquin)FDA Link 01/2021 - 08/2019
2	Dextran SulfateIBA 01/2021 - 03/2012
2	AntioxidantsIBA 01/2020 - 08/2014
2	Caspase 3 (Caspase-3)IBA 01/2020 - 12/2008
2	CalciumIBA 01/2020 - 01/2020
2	Coloring Agents (Dyes)IBA 01/2020 - 09/2008
2	Pharmaceutical PreparationsIBA 01/2020 - 12/2010
2	GastrinsIBA 01/2018 - 11/2011
2	Insulin (Novolin)FDA Link 01/2018 - 11/2011
2	LuciferasesIBA 12/2015 - 04/2014
2	ChemokinesIBA 10/2015 - 11/2011
2	MicronutrientsIBA 10/2015 - 10/2015
2	CateninsIBA 07/2015 - 08/2011
2	PolyaminesIBA 08/2014 - 01/2012
2	SodiumIBA 01/2014 - 10/2013
2	RNA (Ribonucleic Acid)IBA 12/2013 - 10/2002
2	AntibodiesIBA 11/2013 - 12/2005
2	Messenger RNA (mRNA)IBA 10/2013 - 07/2010
2	BerberineIBA 01/2013 - 03/2012
2	Epidermal Growth Factor (EGF)IBA 01/2013 - 04/2009
2	LigandsIBA 08/2011 - 04/2009
2	Interleukin-17 (Interleukin 17)IBA 11/2009 - 10/2005
2	Matrix Metalloproteinases (MMPs)IBA 10/2008 - 10/2003
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2008 - 01/2006
2	beta CateninIBA 01/2008 - 07/2005
2	Interleukin-1beta (Interleukin 1 beta)IBA 09/2006 - 06/2003
1	Deoxycholic Acid (Sodium Deoxycholate)IBA 01/2022
1	Ligases (Synthetase)IBA 01/2022
1	Bile Acids and Salts (Bile Acids)IBA 01/2022
1	UbiquitinIBA 01/2022
1	Clarithromycin (Biaxin)FDA LinkGeneric 01/2021
1	Rifampin (Rifampicin)FDA LinkGeneric 01/2021
1	Metronidazole (Metric)FDA LinkGeneric 01/2021
1	Tetracycline (Achromycin)FDA LinkGeneric 01/2021
1	Neutralizing AntibodiesIBA 01/2021
1	Amoxicillin (Wymox)FDA LinkGeneric 01/2021
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2021
1	Protein Kinases (Protein Kinase)IBA 01/2020
1	Anthocyanins (Anthocyanin)IBA 01/2020
1	MitogensIBA 01/2020
1	methyl jasmonateIBA 01/2020
1	Trefoil Factor-3IBA 01/2020
1	Interleukin-5 (Interleukin 5)IBA 01/2020
1	N(alpha)-carbamoylglutamine-1-amide (NCGA)IBA 01/2020
1	Pepsinogen A (Pepsinogen)IBA 01/2020
1	raptinalIBA 01/2020

Therapy/Procedure

5	Therapeutics 01/2019 - 01/2002
2	Traction 10/2015 - 10/2015
1	Chemoprevention 07/2021
1	Diet Therapy (Therapy, Diet) 01/2020